Do you want to know your ovarian age?-getein.com

Do you want to know your ovarian age?

Admin | 21

February 2024

Do you want to know your ovarian age?

————Anti-Mullerian hormone (AMH) will tell you

As time passes by, women start to show symptoms associated with aging, such as facial sagging, dull skin, forgetfulness, dreaminess, insomnia and irritability.

All of these may be result from the fact that your ovaries are slowly aging. Ovarian reserve function is an important indicator of female reproductive ability, which refers to the potential of the ovaries to produce the number and quality of eggs, and indirectly reflects the function of the ovaries. As age increases, the number of follicles decreases accordingly.

Studies have found that the follicle density of women over 35 years old significantly decreases, and women over 40 years old experience a sharp decline in follicle number. When the ovarian reserve is completely consumed, women enter menopause[1].

Clinical indicators such as hormone testing, ovarian dynamics testing, follicle-stimulating hormone, ovarian and antral follicle ultrasound testing are commonly used to evaluate ovarian reserve function. However, these indicators have requirements for testing time or operational experience. The detection of AMH can effectively solve these problems and become the most direct testing method of ovarian reserve function.

What is AMH?

AMH is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor SF-1, transcription GATA factors, sex-reversal gene DAX1, and follicle-stimulating hormone (FSH)[2]. The more small antral follicles in the ovaries, the higher the concentration of AMH;likewise, as follicles are gradually consumed with age and various factors, AMH concentration will also decrease. By the time of the menopause, the concentration of AMH gradually decreases to zero.

Therefore, examining AMH can effectively assess the "age" of the ovaries.

Applications of AMH

n AMH is a good indicator for evaluating ovarian reserve function and is convenient for examination;

n AMH can predict the age of menopause;

n AMH provides a new diagnostic index for the diagnosis of PCOS;

n AMH has great significance for the diagnosis of premature ovarian failure (POF), ovarian granulosa cell tumor, and gender development abnormalities in children;

n AMH can accurately predict ovarian response and develop individualized stimulation plans before assisted reproductive technology (ART), improving pregnancy rates to a certain extent and reducing risk of complications;

Advantages of AMH examination

How to avoid imbalance of AMH value

The Getein's Chemiluminescence Immunoassay Analyzer, MAGICL 6000 is capable of detecting AMH and other hormones. It is a powerful tool providing accurate diagnosis for patients who have needs for AMH testing！

Women have a unique role as the world’s caregivers and so advancing women’s health must be a shared goal for us all. Getein is committed to women's health with our state-of-the-art products at every stage of her life !